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Pharmacologic Treatments With Lifestyle Modifications in Nonpregnant Adults with Overweight or Obesity in Outpatient Settings: A Living Clinical Guideline From the American College of Physicians (April 2026)

MeSH Terms: Adult; Semaglutide; Tirzepatide; Body Mass Index; Bupropion; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Liraglutide; Naltrexone; Overweight; Topiramate; Sleep Apnea, Obstructive; Contraindications; Internal Medicine; Life Expectancy; Dyslipidemias; Hypertension; Phentermine; Weight Loss; Life Style; Obesity
Guideline Contact: Amir Qaseem ([email protected])
Publication Date: 6/16/2026
Date of Last Evidence Search: 10/2025
Methods Applied: See publication
Publication Scope: Treatment
Countries of Application: United States
Guideline Publication Status: Published
Languages: English
Authors: ACP (US)
Publication Year: 2026

MeSH Terms: Migraine Disorders (C10.228.140.546.399.750); Aspirin (D02.455.426.559.389.657.410.595.176); Anti-Inflammatory Agents; Non-Steroidal (D27.505.954.158.030); Transcranial Magnetic Stimulation (E02.621.820); Headache Disorders; Secondary (C10.228.140.546.699); Acetaminophen (D02.065.199.092.040)
Guideline Contact: Ailsa Stein ([email protected])
Publication Scope: management; prevention; treatment
Countries of Application: United Kingdom
Guideline Publication Status: Published
Languages: English
Authors: SIGN (GB)
Publication Year: 2018

MeSH Terms: Osteoporosis; Postmenopausal (C05.116.198.579.610); Osteoporosis (C05.116.198.579)
Guideline Contact: Andrea Hickman ([email protected])
Publication Scope: implementation; management; treatment
Guideline Publication Status: Published
Languages: English
Authors: Endocrine Society
Publication Year: 2020

Guideline Contact: Ina Kopp ([email protected])
English Title Translation: Pharmacotherapy of idiopathic pulmonary fibrosis (an update) and other progressive pulmonary fibroses
Keywords: Idiopathische Lungenfibrose, progrediente pulmonale Fibrose, progredient fibrosierende interstitielle Lungenerkrankung, Therapie, Nintedanib, Pirfenidon, Idiopathic pulmonary fibrosis,, progressive pulmonary fibrosis, progressive fibrosing interstitial lung disease, therapy, Nintedanib, Pirfenidone
Date for Review: 04/07/2027
Publication Date: 14/11/2022
Publication Scope: management
Countries of Application: Germany
Guideline Publication Status: Published
Languages: German
Authors: AWMF (DE)
Publication Year: 2022

MeSH Terms: Penile Diseases (C12.294.494)
Guideline Contact: Ina Kopp ([email protected])
English Title Translation: Phimosis and paraphimosis in children and adolescents
Date for Review: 28/07/2026
Publication Scope: assessment; management
Countries of Application: Germany
Guideline Publication Status: Under Review
Languages: German
Authors: AWMF (DE)
Publication Year: 2017

MeSH Terms: Behaviour and Behaviour Mechanisms (F01); Exercise Movement Techniques (E02.403)
Publication Scope: counselling
Countries of Application: United Kingdom
Guideline Publication Status: Published
Languages: English
Authors: NICE (UK)
Publication Year: 2013